Table 2.
Intraclass correlation coefficients (ICC*), classic heritability estimates (h2 †) and common environmental variance (CEV‡) for sigma power and spindle density from eight spindle detector algorithms in monozygotic (MZ) and dizygotic (DZ) twin pairs, adjusted§
Characteristic | Variable | ICC_MZ | ICC_DZ | h2 | CEV |
---|---|---|---|---|---|
Total power | S0 | 0.59 | 0.51 | 0.16 | 0.43 |
Average sigma | S1 | 0.76 | 0.58 | 0.37 | 0.39 |
Relative sigma | S2 | 0.81 | 0.43 | 0.77 | 0.04 |
Detector | |||||
Density | a2 | 0.78 | 0.37 | 0.83 | -0.05 |
a3 | 0.81 | 0.44 | 0.72 | 0.08 | |
a4 | 0.57 | 0.53 | 0.08 | 0.49 | |
a5 | 0.66 | 0.30 | 0.71 | -0.05 | |
a7 | 0.77 | 0.38 | 0.78 | -0.01 | |
a8 | 0.75 | 0.16 | 1.18 | -0.43 | |
a9 | 0.77 | 0.40 | 0.75 | 0.02 | |
a10 | 0.76 | 0.34 | 0.83 | -0.08 |
Heritability is calculated using Falconer’s method; values closer to one indicate a pattern expected where variance in a trait is genetically controlled. Negative CEV values suggest that common environmental effects are likely not very important and that genetic dominance effects may be present.
*ICC = σ 2B/[σ 2W + σ 2B].
† h 2, heritability = 2(ICCMZ – ICCDZ).
‡ CEV = (2 × ICCDZ) – ICCMZ.
§Adjusted for age, sex, and age by sex interaction.