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. 2021 Apr 6;49(4):03000605211002999. doi: 10.1177/03000605211002999
Quality indicators (%) Expected performance
Performance
2015 2016 2017 2018 2019
Newborn health education >95.0% 90.92% 93.0% 93.9% 100% 100%
Unsatisfactory DBS samples# <0.5% 0.47% 0.45% 0.44% 0.43% 0.38%
Cards missing essential information# <0.1% 0.35% 0.27% 0.16% 0.09% 0.05%
DBS samples with acceptable transport time# >95.0% 92.9% 94.2% 97.9% 100% 100%
Test reports with an acceptable time from specimen receipt to results reporting# >95.0% 94.8% 95.2% 97.4% 98.4% 98.7%
Test items running IQC 100% 100% 100% 100% 100% 100%
Unsatisfactory testing results in IQC <1.0% 1.1% 0.8% 0.6% 0.3% 0.0%
Newborns with positive results in primary screening <5.0% 3.6% 3.1% 2.2% 2.1% 2.0%
Newborns recalled after positive primary screening# 100% 88.79% 91.1% 93.9% 96.9% 99.6%
Newborns with positive results in secondary screening <1.0% 1.6% 1.1% 0.82% 0.78% 0.72%
Newborns recalled after positive secondary screening# 100% 100% 100% 100% 100% 100%
Newborns with false-negative screening results 0.0% 0.0% 0.0% 0.0% 0.0% 0.0%
Positive predictive value >20.0% 14.2% 14.6% 15.0% 15.2% 15.4%
Annual disease incidence
Newborns that received NBS >95.0% 86.8% 90.8% 95.8% 98.0% 98.6%
Newborns lost to follow-up <0.1% 0.22% 0.20% 0.17% 0.13% 0.08%

#Quality indicators were evaluated monthly. Monthly data from January 2015 to December 2019 were converted to annual metrics for analysis.

Quality indicators were evaluated monthly. Four screening items were included: thyroid stimulating hormone, phenylalanine, glucose-6-phosphate dehydrogenase, and 17α-hydroxyprogesterone. Monthly quality improvement data were converted to annual metrics for analysis.

The annual disease incidence of each screening item was variable; data were not shown.

IQC, internal quality control; DBS, dried blood spot; NBS, newborn screening.