Table 2. Nonhematologic Toxic Events^a.

Toxic event	No. (%) [95% CI] of patients
	Grade 2	Grade 3	Grade 4	Grade 5
CTCAE v 4.0 (primary end point) (20 patients)
Esophagitis	5 (25) [11-47]	0 (0) [0-16]	0	0
RTOG (secondary end point) (25 patients)
Esophagitis	6 (24) [12-43]	0 (0) [0-13]	0	0
CTCAE v 4.0 (secondary end points) (25 patients)
Esophagitis	7 (28) [14-48]	0 (0) [0-13]	0	0
Dysphagia	2 (8)	0	0	0
Dyspepsia	4 (16)	0	0	0
Pneumonitis	2 (8)	0	0	1 (4)
Hypoxia	0	1 (4)	0	0
Pneumonia	1 (4)	0	0	0
Hoarseness	1 (4)	0	0	0
Dyspnea	4 (16)	1 (4)	0	0
Nausea	1 (4)	0	0	0
Fatigue	6 (24)	0	0	0
Dermatitis	5 (20)	0	0	0
Heart failure	0	0	0	1 (4)
Atrial fibrillation	2 (8)	0	0	0
Ventricular tachycardia	0	1 (4)	0	0

Abbreviations: CTCAE v 4.0, Common Terminology Criteria for Adverse Events, version 4.0; RTOG, Radiation Therapy Oncology Group.

^a Toxic events grade 2 or higher possibly, likely, or definitely associated with high-dose radiation therapy.