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4-Substituted tryptamines induce the HTR in C57BL/6J mice. (A) Effect of psilocin (left) and 4-HO-MET (right) on the HTR. Data are presented as group means ± SEM for the entire test session. *, p < 0.05, significant difference from the vehicle control group (Tukey’s test). (B) Comparison of the potencies (ED50 values, in μmol/kg) of 4-hydroxytryptamines (●) and 4-acetoxytryptamines (■) in HTR experiments.
