Table 2. Potency of 4-Acetoxy-N,N-dialkyltryptamines in HTR Experiments Conducted in C57BL/6J Mice.
ED50 (95% CI) |
||
---|---|---|
drug | mg/kg | μmol/kg |
4-AcO-DMT | 0.41 (0.24–0.69) | 1.12 (0.66–1.90) |
4-AcO-MET | 0.44 (0.31–0.63) | 1.17 (0.82–1.67) |
4-AcO-MPT | 0.55 (0.37–0.81) | 1.41 (0.96–2.08) |
4-AcO-MIPT | 1.11 (0.87–1.41) | 2.84 (2.22–3.62) |
4-AcO-DET | 0.71 (0.47–1.07) | 1.81 (1.20–2.74) |
4-AcO-EPT | 0.51 (0.35–0.74) | 1.26 (0.86–1.84) |
4-AcO-DPT | 0.55 (0.35–0.89) | 1.32 (0.82–2.12) |
4-AcO-DIPT | 1.41 (0.95–2.08) | 3.88 (2.63–5.72) |