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Sensitivity of cell lines with acquired resistance to CHK1i. AsPC-1 cells were selected for resistance to MK-8776, SRA737, and LY2606368. Similarly, MDA-MB-231 and H322M cells were selected for resistance to SRA737 and LY2606368. Panel A represents the GI50 values; Panel B represents fold resistance. The numerical values for these data are presented in Table S2.
