Table 2.
Significant independent predictors of early postoperative AF development on multivariate analysis
| Predictors | Predictors for any AF* | Predictors for persistent AF* |
|---|---|---|
| Clinical/surgical predictors | ||
| Low EF (< 60%) | 2.6, 95% CI 2.0–3.4, p < 0.001 | 1.9, 95% CI 1.2–2.9, p = 0.008 |
| Valvular intervention | 2.4, 95% CI 1.8–3.2, p < 0.001 | 2.4, 95% CI 1.6–3.8, p < 0.001 |
| Diabetes | 1.6, 95% CI 1.2–2.2, p = 0.004 | 2.1, 95% CI 1.3–3.3, p = 0.002 |
| COPD | 1.8, 95% CI 1.1–2.9, p = 0.018 | |
| Previous cardiac surgery | 3.1, 95% CI 1.7–5.8, p < 0.001 | |
| Hematological/biochemical predictors | ||
| Low hematocrit (< 35%) | 2.1, 95% CI 1.5–2.9, p < 0.001 | 1.9, 95% CI 1.2–2.9, p = 0.006 |
| Low thrombocyte (< 142 × 109/L) | 5.6, 95% CI 1.1–29.3, p = 0.042 | |
| Low LDL (< 100 mg/dL) | 1.6, 95% CI 1.2–2.1, p = 0.004 | 2.1, 95% CI 1.3–3.1, p = 0.001 |
| High direct bilirubin (> 0.5 mg/dL) | 2.0, 95% CI 1.4–2.9, p < 0.001 | |
| Low GFR (≤ 90 mL/min/1.73m2) | 1.6, 95% CI 1.1–2.4, p = 0.026 | |
| High CRP (> 5 mg/L) | 2.0, 95% CI 1.2–3.2, p = 0.004 | 2.7, 95% CI 1.5–4.7, p = 0.001 |
| High HbA1c (> 6.5%) | 2.0, 95% CI 1.3–3.1, p = 0.001 | |
AF, atrial fibrillation; COPD, chronic obstructive pulmonary disease; CRP, C-reactive protein; EF, ejection fraction; GFR, glomerular filtration rate; LDL, low-density lipoprotein
*Odds ratio, 95% confidence interval, p value