Fig. 6.

SeMet inhibits T-2 toxin-induced hepatocyte apoptosis. Nuclei of apoptotic cells were labeled with green fluorescence by TUNEL staining. All the nuclei were stained blue by DAPI and the nuclei of apoptotic cells were stained green by TUNEL. Compared with the control group, the number of apoptotic cells in the T-2 toxin group increased significantly. After low-dose SeMet pretreatment, the number of apoptotic cells decreased significantly. However, as the dose of SeMet increased, the number of apoptotic cells in the medium-dose and high-dose groups gradually increased. a: control group, b T-2 toxin group c: low-dose SeMet+T-2 toxin group, d: medium-dose SeMet+T-2 toxin group, e: high-dose SeMet+T-2 toxin group. Magnification is 250× and scale is 100 μm