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. 2021 Mar 12;4(2):953–965. doi: 10.1021/acsptsci.1c00035

Table 2. Determination of Sensitivity and Specificity of the Indirect Indicators of Toxicity Incomparison to Pathology.

parameter % sensitivity % specificity
Kidney Pathology
weight loss 87 95
BUN 74 97
Liver Pathology
weight loss 85 74
AST 14 90
ALKP 85 86
ALT 28 95