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. 2021 Feb 17;4(2):848–857. doi: 10.1021/acsptsci.1c00012

Table 2. Polypharmacy List and Combination of Drugs Detected in Pregnant Human Sera.

polypharmacy effect on 7-DHC
two or more DHCR7-inhibiting drugs nb 7-DHCa (FOC)
ARI + SER 1 1.2
TRZ + SER 1 1.3
BUP + BUS 1 48.1
FLX + MTP + TRZ 1 8.6
a

Levels of 7-DHC shown as fold over control (FOC) with a baseline of all samples without 43 samples containing 7-DHC-elevating medications.

b

Number of samples with the corresponding combination of medications (n).