Table 2. Polypharmacy List and Combination of Drugs Detected in Pregnant Human Sera.
polypharmacy
effect on 7-DHC | ||
---|---|---|
two or more DHCR7-inhibiting drugs | nb | 7-DHCa (FOC) |
ARI + SER | 1 | 1.2 |
TRZ + SER | 1 | 1.3 |
BUP + BUS | 1 | 48.1 |
FLX + MTP + TRZ | 1 | 8.6 |
Levels of 7-DHC shown as fold over control (FOC) with a baseline of all samples without 43 samples containing 7-DHC-elevating medications.
Number of samples with the corresponding combination of medications (n).