Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 15;12:604713. doi: 10.3389/fphar.2021.604713

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Paci, Koivumäki, Lu, Gallacher, Passini and Rodriguez.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effects of flecainide I on the three in silico models for the two tested concentrations (C1 and C2). (A) Comparison of action potentials, Ca²⁺ transients and ion currents. (B) Detail of the Koivumäki2018 traces, showing a residual activity due to spontaneous Ca²⁺ releases from the sarcoplasmic reticulum that activate the inward component of I_NCX.