NAFL-related scores and histology. (a) NAFL activity score (NAS)
and individual scores for contributions by steatosis, fibrosis, lobular
inflammation, and hepatocellular ballooning determined from all animals
in the different treatment groups. Post-treatment scores were compared
with pretreatment scores for each individual animal, and the change
in the score is shown as improvement (lower score), no change, or
worsening (higher score). (b) Representative immune-histochemistry
images from post-treatment liver histology samples for the different
treatment groups.