Table 3. Means and Standard Deviations of Acute Subjective Experiences and Persisting Effects among the Total Sample and among Those with Alcohol Misuse/AUD or Drug Misuse/DUD as a Function of Whether Conditions Improved or Did Not Improve Following Mescaline Usea.
| alcohol
misuse/AUD (n = 72) |
drug
misuse/DUD (n = 85) |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| variables | total sample (N = 452) | better (n = 48) | no change or worse (n = 2) | t-stat | d | better (n = 58) | no change or worse (n = 27) | t-stat | d |
| psychological insight (PIQ) | 2.4(1.2) | 3.2(1.0) | 1.9(1.2) | –5.0*** | 1.2 | 3.2(0.9) | 2.0(1.0) | –5.7*** | 1.3 |
| mystical type effects (MEQ) | 3.2(1.1) | 3.8(0.8) | 3.0(1.1) | –3.5** | 0.8 | 3.8(0.8) | 2.9(1.2) | –4.4*** | 0.9 |
| challenging effects (CEQ) | 0.6(0.7) | 0.7(0.6) | 0.5(0.4) | –1.2 | NS | 0.8(0.6) | 0.6(0.4) | –0.9 | NS |
| ego dissolution (EDI) | 2.4(1.3) | 3.0(1.1) | 2.2(1.3) | –2.5* | 0.7 | 2.9(1.2) | 2.1(1.1) | –2.7** | 0.7 |
| personal meaning | 4.6(1.4) | 5.1(1.3) | 4.3(1.8) | –2.3* | 0.5 | 4.8(1.3) | 4.2(1.5) | –2.0 | NS |
| spiritual significance | 4.4(1.9) | 5.2(1.4) | 4.0(2.1) | –3.0** | 0.7 | 4.9(1.4) | 3.6(2.2) | –3.4** | 0.7 |
| psychologically challenging | 2.8(2.1) | 3.3(2.3) | 2.4(2.4) | –1.5 | NS | 3.0(2.0) | 2.1(1.9) | –1.9 | NS |
| psychologically insightful | 4.1(1.7) | 5.0(1.5) | 3.7(2.1) | –3.0** | 0.7 | 4.7(1.5) | 3.5(1.6) | –3.4** | 0.8 |
| well-being/life satisfaction | 2.1(1.1) | 2.6(0.8) | 1.6(1.1) | –5.0*** | 1.0 | 2.5(0.7) | 1.6(1.2) | –4.4*** | 0.9 |
| life’s purpose | 1.8(1.1) | 2.5(0.8) | 1.2(1.2) | –5.6*** | 1.3 | 2.3(1.0) | 1.3(1.1) | –4.1*** | 1.0 |
| life’s meaning | 1.8(1.2) | 2.4(0.8) | 1.1(1.1) | –6.0*** | 1.4 | 2.1(1.0) | 1.0(1.0) | –5.4*** | 1.1 |
| social relationships | 1.6(1.3) | 2.3(0.8) | 0.8(1.3) | –5.9*** | 1.4 | 2.2(0.9) | 0.9(1.6) | –4.6*** | 1.0 |
| attitudes about life | 1.9(1.1) | 2.5(0.7) | 1.3(1.5) | –4.8*** | 1.0 | 2.4(0.8) | 1.5(1.5) | –3.8*** | 0.8 |
| attitudes about self | 1.8(1.1) | 2.4(0.9) | 1.0(1.1) | –5.7*** | 1.4 | 2.3(0.9) | 1.2(1.1) | –4.9*** | 1.1 |
| relationship to nature | 2.0(1.0) | 2.7(0.7) | 1.5(1.1) | –5.6*** | 1.3 | 2.6(0.7) | 1.6(1.1) | –5.2*** | 1.1 |
| behaviors | 1.5(1.1) | 2.3(0.9) | 0.8(1.3) | –5.5*** | 1.3 | 2.1(1.0) | 0.9(1.4) | –4.5*** | 1.0 |
| how spiritual you are | 1.6(1.2) | 2.3(1.0) | 1.2(1.1) | –4.4*** | 1.1 | 2.1(1.0) | 1.2(1.2) | –3.6** | 0.8 |
| attitudes about death | 1.2(1.2) | 1.8(1.3) | 0.7(1.1) | –3.9*** | 0.9 | 1.6(1.3) | 0.8(1.2) | –3.0** | 0.6 |
| views re: true nature of reality | 1.7(1.2) | 2.4(1.0) | 1.4(1.1) | –3.6** | 1.0 | 2.1(1.1) | 1.4(1.2) | –2.8** | 0.6 |
a
*p < 0.05, **p < 0.01, ***p < 0.001. Note: Cohen’s d was calculated to estimate effect sizes and is interpreted as 0.2 = small, 0.5 = medium, 0.8 = large. Scores on the PIQ, MEQ, and CEQ range from 0 to 5, and ratings of subjective well-being can range from −3 to +3.