Table 3.
Univariate and Multivariate Regression Analysis of FMD‐AUC 120 and ΔFMD
| FMD‐AUC120 | ΔFMD | |||||||
|---|---|---|---|---|---|---|---|---|
| Covariate | Univariate | Multivariate | Univariate | Multivariate | ||||
| r | P Value | β | P Value | r | P Value | β | P Value | |
| Age | −.20 | .001 | −.17 | .014 | −.09 | .132 | −.06 | .435 |
| Body mass index | −.03 | .640 | – | – | −.08 | .182 | – | – |
| Office systolic blood pressure | −.16 | .011 | .01 | .921 | −.07 | .249 | −.04 | .664 |
| Office diastolic blood pressure | −.02 | .570 | – | – | .02 | .725 | – | – |
| Office pulse rate | −.02 | .805 | – | – | .02 | .793 | – | – |
| Home systolic blood pressure | −.23 | <.001 | −.27 | .003 | −.13 | .041 | −.06 | .513 |
| Home diastolic blood pressure | −.06 | .350 | – | – | −.02 | .780 | – | – |
| Home pulse rate | −.02 | .802 | – | – | −.01 | .906 | – | – |
| Total cholesterol | .07 | .282 | – | – | .02 | .721 | – | – |
| Log triglyceride | −.05 | .432 | – | – | −.02 | .703 | – | – |
| Log fasting glucose | −.08 | .184 | – | – | .00 | .984 | – | – |
| Log hemoglobin A1c | .00 | .999 | – | – | .05 | .427 | – | – |
Multiple linear regression analysis was performed to determine the variables with independent significant association with flow‐mediated vasodilation (FMD) response calculated as the area under the dilation curve during 120 seconds after deflation (FMD‐AUC120). Age, sex, office and home systolic blood pressure, and variables with P<.05 in univariate analysis were included in the model (calcium channel blocker use).