Table 2.
Baseline 24‐Hour Ambulatory SBP and DBP and Serum Potassium Concentration Response to Low‐Salt, High‐Salt, and High‐Salt With Potassium Supplementation Interventions for Total Patients, Salt‐Sensitive Patients, and Non–Salt‐Sensitive Patients
| Baseline | Low‐Salt | High‐Salt | High‐Salt+Potassium Supplementation | P Valuea | |
|---|---|---|---|---|---|
| 24‐h ambulatory SBP, mm Hg | |||||
| Total, N=155 | 123.0 (111.0–133.0) | 113.0 (105.0–123.0)b | 131.0 (115.0–139.0)b,c | 121.0 (109.0–131.0)c,d | <.001 |
| Salt‐sensitive, n=85 | 125.0 (113.0–133.0) | 113.0 (105.0–121.0)b | 133.0 (121.0–141.0)b,c | 125.0 (113.0–131.0)c,d | <.001 |
| Non–salt‐sensitive, n=70 | 117.0 (107.0–129.0) | 112.0 (103.0–125.0)b | 119.0 (109.0–133.0)b,c | 115.0 (105.0–127.0)c,d | <.001 |
| 24‐h ambulatory DBP, mm Hg | |||||
| Total, N=155 | 77.0 (69.0–83.0) | 71.0 (67.0–79.0)b | 81.0 (73.0–85.0)b,c | 77.0 (71.0–81.0)c,d | <.001 |
| Salt‐sensitive, n=85 | 77.0 (71.0–83.0) | 73.0 (67.0–77.0)b | 81.0 (77.0–85.0)b,c | 77.0 (73.0–81.0)c,d | <.001 |
| Non–salt‐sensitive, n=70 | 75.0 (69.0–83.0) | 71.0 (67.0–79.0)b | 79.0 (71.0–85.0)b,c | 75.0 (69.0–81.0)c,d | <.001 |
| Serum potassium concentration, mmol/L | |||||
| Total, N=155 | 4.40 (4.20–4.70) | 4.64 (4.49–4.82)b | 4.40 (4.10–4.90)c | 4.95 (4.80–5.17)b,c,d | <.001 |
| Salt‐sensitive, n=85 | 4.30 (4.00–4.70) | 4.59 (4.49–4.84)b | 4.40 (4.10–4.70)c | 4.95 (4.72–5.18)b,c,d | <.001 |
| Non–salt‐sensitive, n=70 | 4.59 (4.30–4.80) | 4.69 (4.54–4.82) | 4.55 (4.20–4.90) | 4.99 (4.88–5.14)b,c,d | <.001 |
Abbreviations: DBP, diastolic blood pressure; SBP, systolic blood pressure. aFriedman test. Post‐hoc Wilcoxon signed‐rank test using Bonferroni correction: b P<.05 vs baseline, c P<.05 vs low‐salt intervention, d P<.05 vs high‐salt intervention.