Fig. (2).

The protective role of polydatin against dementia-relating disorders. The lines with an arrowhead indicate facilitation. The lines with a blocked end indicate inhibition. The dashed lines indicate the hypothetical pathways that might be regulated by polydatin. Aβ, amyloid-β; CDK5, cyclin-dependent kinase 5; mAChRs, muscarinic acetylcholine receptors; nAChRs, nicotinic acetylcholine receptors; NR2B, NMDA receptor 2B subunit; p-tau, phosphorylated tau. (A higher resolution / colour version of this figure is available in the electronic copy of the article).