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editorial
. 2021 May;111(5):820–825. doi: 10.2105/AJPH.2020.306147

TABLE 2—

Hypothetical Effects of Salt Reduction on Blood Pressure and Cardiovascular Mortality From the Population Perspective

Cause-Specific Mortality
Stroke Ischemic Heart Disease Other Vascular Total
Prevalence of “exposure” to BPa 1 1 1
Reduction of systolic BP (mm Hg) with low-salt diet 4.2 4.2 4.2
RR of mortality that relates to 4.2-mm BP reductionb 0.84 0.88 0.86
Mortality base rate per 1000 0.47 1.00 0.50
Intervention mortality rate per 1000 0.39 0.88 0.43
Risk difference per 1000c −0.08 −0.12 −0.07
Number needed to treat 13 084 8239 14 764
Deaths prevented per 30 million population 2293 3641 2032 7966

Note. BP = blood pressure; RR = relative risk.

a

Prevalence of blood pressure is set at 1 because everyone is exposed.

b

Conversion based on hazard ratios per 20-mm decrease in systolic BP provided by Lewington et al.26

c

RD = BR × (RR-1) (Newcombe and Bender19)