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. 2021 Apr 9;43:12. doi: 10.1186/s41021-021-00186-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Human stomach from which mucosal tissue samples were taken from multiple sites. (a) Example of macroscopic view after multisite sampling in the stomach, resected for gastric cancer in this case. Mucosal tissues were taken: 10 from the nontumor area and 2 from the tumor area (N1-N10, T1-T2). (b) A histogram of the numbers of sampling sites of nontumor areas in gastric cancer cases. The x-axis represents the sample size (numbers taken for DNA analysis) taken from an individual and the y-axis represents the number of individuals with that sample size. Among the 59 cases in this study, the maximum number of samples collected from one case was 27