Table 2.

Summary of the meta-analysis of the association of APOA gene polymorphisms with hyperlipidemia

SNP	Analysis model	Genotype model	Heterogeneity(I2/P)	OR (95%CI)	P	Publication bias P
APOA5–1131 T>C	A	C vs T	73.9%/ < 0.001	1.996(1.529 ~ 2.606)	< 0.001	0.353
	D	TC + CC vs TT	71.2%/ < 0.001	2.179(1.565 ~ 3.035)	< 0.001	0.258
	R	CC vs TC + TT	5.5%/ 0.390	2.790(2.055 ~ 3.789)	< 0.001	0.991
	C	CC vs TT	45.7%/ 0.056	3.604(2.589 ~ 5.017)	< 0.001	0.899
		TC vs TT	67.2%/ 0.001	1.932(1.395 ~ 2.674)	< 0.001	0.465
APOA1-75 bp	A	A vs G	1.2%/ 0.400	1.228(1.067 ~ 1.413)	0.004	0.086
	D	AA+GA vs GG	0.0%/ 0.704	1.246(1.056 ~ 1.471)	0.009	0.067
	R	AA vs GA + GG	15.9%/ 0.313	1.458(0.976 ~ 2.180)	0.066	0.086
	C	AA vs GG	17.4%/ 0.304	1.520(1.008 ~ 2.291)	0.046	0.086
		GA vs GG	0.0%/ 0.828	1.212(1.020 ~ 1.439)	0.029	0.221
APOA1 + 83 bp	A	T vs C	0.0%/ 0.472	0.928(0.771 ~ 1.116)	0.425	0.440
	D	TT + TC vs CC	0.0%/ 0.478	0.950(0.780 ~ 1.157)	0.607	0.371
	R	TT vs TC + CC	0.0%/ 0.799	0.310(0.076 ~ 1.271)	0.104	0.315
	C	TT vs CC	0.0%/ 0.775	0.308(0.075 ~ 1.259)	0.101	0.346
		TC vs CC	0.0%/ 0.607	0.967(0.793 ~ 1.180)	0.740	0.466

A allelic model; D dominant model; R recessive model; C codominant model; Publication bias P: using Begg’s or Egger’s tests