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. 2021 Apr 9;22:14. doi: 10.1186/s12863-021-00968-1

Table 8.

Summary of the meta-analysis of the association of APOE gene polymorphisms with hyperlipidemia

Genotype model Heterogeneity(I2/P) OR(95%CI) P publication bias P
E2/E2 0.0%/0.634 1.746(1.081 ~ 2.819) 0.023 0.131
E2/E3 50.3%/0.001 1.076(0.883 ~ 1.311) 0.467 0.400
E2/E4 0.0%/0.790 1.693(1.227 ~ 2.336) 0.001 0.054
E3/E4 67.8%/< 0.001 1.578(1.276 ~ 1.951) < 0.001 0.073
E4/E4 2.7%/ 0.424 2.346(1.723 ~ 3.195) < 0.001 0.851

Publication bias P: using Begg’s or Egger’s tests