Table 5.

Summary table of findings in the network meta-analysis for post-extubation respiratory failure

NMA network meta-analysis, NPPV noninvasive positive-pressure ventilation, HFNC high-flow nasal cannula, COT conventional oxygen therapy, SOF summary of findings, SUCRA surface under the cumulative ranking

NMA-SoF table definitions

^*Lines represent direct comparisons

^**Estimates are reported as risk ratio. CI: confidence interval

^***Anticipated absolute effect. Anticipated absolute effect compares two risks by calculating the difference between the risks of the intervention group with the risk of the control group

^****Rank for efficacy outcome is presented. Rank statistics is defined as the probabilities that a treatment out of n treatments in a network meta-analysis is the best, the second, the third and so on until the least effective treatment

GRADE Working Group grades of evidence (or certainly in the evidence)

High quality: We are very confident that the true effect lies close to that of the estimate of the effect

Moderate quality: We are moderately confident in the effect estimate: The true effect is likely close to the estimate of the effect, but there is a possibility that it is substantially different

Low quality: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect

Very low quality: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate effect

Explanatory footnotes

^aConfidence interval extends into clinically important effects in both directions

^bConfidence interval extends into clinically important effects