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. 2021 Apr 9;20:177. doi: 10.1186/s12936-021-03709-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Dynamics of parasite and gametocyte in P. falciparum at baseline and endpoint. At baseline, P. falciparum prevalence was 6% (52/811) by microscopy and/or PCR. Half of these 52 subjects were positive by microscopy thus treated (54% = 28/52, ■), and 46% (24/52) were submicroscopic and untreated (□). At the endpoint, only two of each microscopic and submicroscopic group were positive. However, 46 subjects other than the mentioned groups were detected positive by microscopy (n = 32) or PCR (n = 14) ( ). Forty of these 46 subjects had data at baseline: 73% (n = 29) were parasite negative and 27% (n = 11) were infected with other species (P. vivax). Furthermore, similar pattern was observed in gametocyte. At baseline, gametocyte prevalence was 2% (19/803). Seventy-nine percent (15/19) had microscopic parasite and treated ( ), and 21% (4/19) had submicroscopic thus untreated ( ). At the endpoint, only one submicroscopic parasite remained positive. However, 22 subjects other than the mentioned groups were positive for gametocyte ( ). Twenty of these 22 subjects were negative at baseline while two had no data

Inline graphic — Dynamics of parasite and gametocyte in P. falciparum at baseline and endpoint. At baseline, P. falciparum prevalence was 6% (52/811) by microscopy and/or PCR. Half of these 52 subjects were positive by microscopy thus treated (54% = 28/52, ■), and 46% (24/52) were submicroscopic and untreated (□). At the endpoint, only two of each microscopic and submicroscopic group were positive. However, 46 subjects other than the mentioned groups were detected positive by microscopy (n = 32) or PCR (n = 14) ( ). Forty of these 46 subjects had data at baseline: 73% (n = 29) were parasite negative and 27% (n = 11) were infected with other species (P. vivax). Furthermore, similar pattern was observed in gametocyte. At baseline, gametocyte prevalence was 2% (19/803). Seventy-nine percent (15/19) had microscopic parasite and treated ( ), and 21% (4/19) had submicroscopic thus untreated ( ). At the endpoint, only one submicroscopic parasite remained positive. However, 22 subjects other than the mentioned groups were positive for gametocyte ( ). Twenty of these 22 subjects were negative at baseline while two had no data