Table 1.
Descriptive characteristics of the Framingham Offspring Study participants included in this integration analysis
| Variable | Methylation | Gene expression |
|---|---|---|
| n = 2055 | n = 914 | |
| Agea | 65.23 (8.59) | 64.48 (8.43) |
| Sex, male, n (%) | 871 (42.38) | 336 (36.76) |
| Total cholesterol, mg/dLa | 190.16 (35.79) | 192.30 (35.62) |
| HDL-C, mg/dLa,c | 58.91 (18.45) | 59.51 (17.96) |
| Triglycerides, mg/dLb,c | 100 (73,138) | 101 (73,140.75) |
| SBP, mmHga,c | 125.19 (16.83) | 125.35 (16.97) |
| DBP, mmHga,c | 72.31 (9.90) | 72.65 (10.16) |
| Glucose, mg/dLb | 101 (94,109) | 100 (93,108) |
| Smokers, n (%) | 199 (9.68) | 96 (10.50) |
| BMI, kg/m2a,c | 27.99 (5.30) | 27.88 (5.33) |
| Waist, cma,c | 100.56 (14.47) | 100.08 (14.67) |
| CHD, n (%) | 83 (4.04) | 28 (3.06) |
| CVD, n (%) | 201 (9.78) | 79 (8.64) |
SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, Waist waist circumference, CHD coronary heart disease, CVD cardiovascular disease
aMean (standard deviation)
bMedian (interquartile range)
cHDL-C, high-density lipoprotein cholesterol