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. 2021 Apr 7;16(1):570–580. doi: 10.1515/med-2021-0254

Figure 5.

Figure 5

circ_0026344 regulated CRC development by binding to miR-645 in propofol-treated SW480 and LOVO cells. (a) miR-645 expression was detected by qPCR in SW480 and LOVO cells transfected with anti-NC or anti-miR-645. SW480 and LOVO cells were treated with propofol + si-NC, propofol + si-circ#1, propofol + si-circ#1 + anti-NC, and propofol + si-circ#1 + anti-miR-645, respectively. (b–d) Cell proliferation was determined by CCK8 and colony formation assays. (e) Cell apoptosis was detected by flow cytometry assay. (f and g) Cell migration and invasion were detected by transwell assay. Significant differences were compared with Student’s t-test (a) or ANOVA (b–g). **P < 0.01.