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. 2021 Apr 6;9:e11026. doi: 10.7717/peerj.11026

Table 2. Findings of included studies.

Author, Year Instrument Results Time assessment Success in the evaluation, n (%) Conclusions
Liu et al. (2020) FIM Pre-Intervention:
FIM score CG: 109.3 ± 10.7; IG: 109.2 ± 13
Post-intervention:
FIM score CG: 108.9 ± 10.1; IG: 109.4 ± 11.1
Before and after pulmonary rehabilitation 72 (78.2%) Six-week respiratory rehabilitation can improve respiratory function, QoL, and anxiety, but does not improve the FIM score of elderly patients with COVID-19
Bousquet et al. (2020) ADL Score ADL score ≤ 5/6: 54 (50%)
IADL score ≤ 3/4: 68 (63%)
Before hospitalization 108 (90%) ADL-dependency before hospitalization, serum levels of D-Dimers and LDH, and the absence of anticoagulation were the factors independently associated with 1-month mortality in older inpatients with COVID-19
Sakai et al. (2020) BI RRG: BI mobility score 15; total score 90
DRG: BI mobility score 10 (range 0–15); total BI score 70 (range 0–85)
At hospital discharge (before and after rehabilitation) 43 (97.7%) Both mobility and total BI scores improved in both groups after intervention
Zerah et al. (2020) ADL Score Mean ADL score 4 (IQR2-6)
ADL score (Non-survivors) 3 (IQR 1–6)
ADL score (Survivors) 4.5 (IQR 2–6)
During hospital stay 821 (93.5%) Hospital mortality was associated with lower ADL scores (ADL < 4)
Curci et al. (2020) BI Total BI score: 45.2 ± 27.6
FIO2 ≥ 21% and <40% (n = 13)
BI score 53.3 ± 29.3
FiO2 ≥ 40% and <60% (n = 19)
BI score: 39.6 ± 25.7
At admission to the rehabilitation unit 32 (88.8%) COVID-19 patients had severe disability. Only 14 were able to walk
Belli et al. (2020) BI At entry rehabilitation institute: 67%: ≤60 BI score
At discharge rehabilitation institute: 47.5%: ≤60 BI score
At entry and discharge of rehabilitation institute 103 (89.5%) Physical functioning and performance of ADLs were still significantly impaired at discharge to their home
Mcloughlin et al. (2020) CFS Pre Delirium: 153/166 CFS score
Post Delirium: 97/166 CFS score
During hospital stay and 4 weeks after hospital discharge 71 (86.59%) Delirium was associated with functional impairments in the mid-term
Agarwal et al. (2020) mRS LCM: 5 (IQR 4–5) mRS score
OMRIBF: 4 (IQR 2–5) mRS score
At hospital discharge 115 (100%) LCM was associated with critical illness, mortality and worse functional outcome in patients with COVID-19
Halpin et al. (2020) EQ-5D-5L 22ICUG participants (22%) experiencing new problems in mobility, self-care or usual activities. Mean 48 ± 10.3 days post hospital discharge 100 (100%) COVID-19 was associated with illness-related fatigue, breathlessness and psychological distress leading to a significant drop in quality of life

Note:

Abbreviations: ADL: Activities of daily living; BI: Barthel Index; CFS: Composite Functional Score; CG: control group; CT: computerized tomography; DRG: direct rehabilitation group; FIM: Functional Independence Measure; IADL: Instrumental Activities of daily living; ICUG: Intensive care unit group; IG: intervention group; IQR: Inter-quartile range; LCM: Leukoencephalopathy and/or Cerebral Microbleeds; LDH: Lactate Dehydrogenase; mRS: Modified Rankin Scale; NI: no intervention; NR: not reported; OMRIBF: Other Magnetic Resonance Imaging Brain Findings; qSOFA: quick Sequential Organ Failure Assessment score; RRG: remote rehabilitation group.