Table 2.
Diagnostic value of CTIS and CO-RADS on chest CT for the diagnosis of COVID-19 infection using RT-PCR as the standard of reference.
| TP | FP | TN | FN | SENSITIVITY* (95% CI) | SPECIFICITY* (95% CI) | PPV* (95% CI) | NPV* (95% CI) | ACCURACY* (95% CI) | AUC (95% CI) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Moderate or Severe CTIS | 57 | 43 | 89 | 11 | 83.8 (72.9–91.6) | 67.4 (58.7–75.3) | 57.0 (50.4–63.38) | 89.00 (82.3–93.4) | 73.0 (66.3–79.0) | 0.756 (0.686–0.826) |
| Severe CTIS | 52 | 24 | 108 | 16 | 76.5 (64.6–85.9) | 81.8 (74.2–88.0) | 68.4 (59.6–76.1) | 87.1 (81.4–91.3) | 80.0 (73.8–85.3) | 0.791 (0.722–0.778) |
| CO-RADS 4/5 | 60 | 20 | 112 | 8 | 88.2 (78.1–94.8) | 84.9 (77.6–90.5) | 75.0 (66.5–81.9) | 93.3 (87.9–96.4) | 86.0 (80.4–90.5) | 0.865 (0.809–0.922) |
| Mixed Severe CTIS and/or CO-RADS 4/5 | 60 | 25 | 107 | 8 | 88.2 (78.1–94.8) | 81.1 (73.3–87.3) | 70.6 (62.5–77.5) | 93.0 (87.4–96.3) | 83.5 (77.6–88.4) | 0.846 (0.787–0.906) |
TP: true positive, FP: false positive, TN: true negative, FN: false negative, PPV: positive predictive value, NPV: negative predictive value, AUC: area under the curve, CI: confidence interval. Unless otherwise specified data are numbers. CTIS: CT involvement score.
* Data are percentages.