Table 6.
Rank | p | CCLC | Target NSC | Small Molecules | MW: (g/mol) | Correlation | CCLC | Standard Anti-cancer |
---|---|---|---|---|---|---|---|---|
1 | 0.89 | 57 | 758440 | Niclosamide (USAN) | 327.12 | 0.42 | 56 | 4-ipomeanol |
2 | 0.84 | 55 | 50681 | N-(2-ethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide | 307.3 | 0.39 | 55 | Bryostatin 1 |
3 | 0.77 | 54 | 772889 | MK-2048 | 461.9 | 0.35 | 44 | Flavoneacetic Acid Ester |
4 | 0.76 | 57 | 757391 | Dichlorophene | 269.1 | 0.34 | 55 | Tamoxifen |
5 | 0.76 | 57 | 37202 | Celcot RN | 313.3 | 0.33 | 56 | Rapamycin |
6 | 0.72 | 55 | 37188 | Azotol OT | 277.3 | 0.33 | 56 | Flavoneacetic Acid |
7 | 0.7 | 57 | 37608 | Naphthol AS-AN | 308.2 | 0.32 | 47 | Morpholino-ADR |
8 | 0.68 | 56 | 777205 | 3-(4-chloro-2-fluorophenyl)-2H-chromen-2-one | 274.6 | 0.32 | 44 | Spirohydantoin Mustard |
9 | 0.67 | 57 | 50686 | Naphtanilide TR | 311.8 | 0.31 | 56 | SR2555 (Nitroimidazole) |
10 | 0.67 | 48 | 13235 | Dibromosalicil | 400.0 | 0.31 | 53 | Piperazine Alkylator |
11 | 0.64 | 57 | 766722 | 3-(1H-benzimidazol-2-yl)-6-hexyl-2-(2-methylphenyl)iminochromen-7-ol | 451.6 | 0.3 | 57 | Rapamycin |
12 | 0.62 | 57 | 81947 | Dibromsalan (USAN) | 3.71.0 | 0.29 | 56 | Merbarone |
13 | 0.62 | 56 | 760057 | Nitazoxanide (USAN) | 307.2 | 0.29 | 46 | O6-Methylguanine |
14 | 0.62 | 52 | 705084 | 4-Butanediyldihydroguaiaretic | 330.4 | 0.29 | 56 | DTIC |
15 | 0.61 | 57 | 12969 | N-(3-Chlorophenyl)-3-hydroxynaphthalene-2-carboxamide | 297.7 | 0.29 | 56 | Fluorodopan |
P, Pearson’s correlation coefficient; CCLC, common cell lines count; MW, molecular weight.