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. 2021 Feb 23;25(7):3284–3299. doi: 10.1111/jcmm.16399

FIGURE 3.

FIGURE 3

ITPP‐induced reduction of immunosuppressive myeloid‐derived and macrophage cell populations inside the tumour CD45+ cell population (A, B). ITPP treatment reduced the proportions of CD45+ CD11b+ Gr1+ MDSCs in B16F10 Luc melanoma (A) and tended to increase CD45+ CD11c+ CD206− M1 macrophages (B). Data represent the median values of five experimental mice from three separate experiments (*P < .05). (C, D) ITPP treatment decreased CD45+ CD11c+ CD206+M2 macrophages in B16F10Luc melanoma (C). Data represent the median values of five experimental mice from three separate experiments (*P < .05, **P < .01) in 4T1mammary carcinoma (D). Data represent the means of six experimental mice from three separate experiments (*P < .05)