FIGURE 6.

AG490 eliminates the cardioprotection of EIP‐22. A, The protein levels of p‐JAK2 and p‐STAT3 were inhibited whereas cells were treated with AG490 in H/R model. B, Quantification data of expression level of p‐JAK2 and p‐STAT3 in H/R model. C, The protein levels of p‐JAK2 and p‐STAT3 were inhibited whereas cells were treated with AG490 in H₂O₂ model. D, Quantification data of expression level of p‐JAK2 and p‐STAT3 in H₂O₂ model. E, The detection of cell viability in H/R model. F, The detection of cell viability in H₂O₂ model. G, The detection of LDH level in H/R model. H, The detection of LDH level in H₂O₂ model. I, The proteins related to apoptosis were detected in H/R model by Western blot analysis. J, Quantification data of Western blot analysis. K, The proteins related to apoptosis were detected in H₂O₂ model by Western blot analysis. L, Quantification data of Western blot analysis. The data represent means ± SD. ^** P < .01 vs. the Scr group, ^*** P < .001 vs. the Scr group, ^# P < .05 vs. the H/R + Scr or H₂O₂ + Scr group, ^## P < .01 vs. the H/R + Scr or H₂O₂ + Scr group, ^& P < .05 vs. the H/R + EIP‐22 or H₂O₂ + EIP‐22 group, ^&& P < .01 vs. the H/R + EIP‐22 or H₂O₂ + EIP‐22 group