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. Author manuscript; available in PMC: 2021 Apr 9.
Published in final edited form as: Genes Brain Behav. 2020 Apr 14;19(7):e12654. doi: 10.1111/gbb.12654

FIGURE 3.

FIGURE 3

Grm7−/− mice exhibit repetitive paw clasping along with deficits in motor coordination and strength. Quantification of forepaw, A, and hindpaw, B, clasping over time. N = 10 Grm7+/+ (6 female, 4 male), 15 Grm7+/− (10 female, 6 male), 14 Grm7−/− (8 female, 6 male). C, Forepaw gait parameters measured by Treadscan system. N = 10 Grm7+/+ (5 female, 5 male), 14 Grm7+/− (5 female, 9 male), 12 Grm7−/− (7 female, 5 male). D, Latency to fall from an accelerating rotarod over 3 days. E, Latency to fall from rotarod normalized to day 1. F, Lack of correlation of latency to fall from rotarod on day 3 with weight. r values shown in inset. For panels (D) to (F), N = 17 Grm7+/+ (9 female, 8 male), 25 Grm7+/− (15 female, 10 male), 24 Grm7−/− (13 female, 11 male). G, Quantification of forepaw grip strength. N = 10 Grm7+/+ (6 female, 4 male), 15 Grm7+/− (10 female, 6 male), 14 Grm7−/− (8 female, 6 male). *P < .05, **P < .01, ***P < .001, ****P < .0001