Table 5.
Adverse Events Reported Between 1 and 6 Months After Fecal Microbiota Transplantation
| Adverse event | n (%) |
|---|---|
| New diagnoses | |
| No | 125 (80) |
| Yesa | 21 (13) |
| Irritable bowel syndrome, diarrhea | 2 (1) |
| Ulcerative colitis | 2 (1) |
| Otherb | 22 (14) |
| Not reported | 10 (6) |
| Serious infections | |
| No | 140 (90) |
| Yesa | 6 (4) |
| Pneumonia | 1 (<1) |
| UTI | 1 (<1) |
| Campylobacter infection | 1 (<1) |
| Cellulitis | 1 (<1) |
| Infected AV fistula/MRSA bacteremia | 1 (<1) |
| Streptococcus pharyngitis | 1 (<1) |
| Pneumonia/acute kidney injury with or without aspiration pneumonia/UTI | 1 (<1) |
| Not reported | 10 (6) |
| Hospitalizations | |
| No | 126 (81) |
| Yesa | 30 (19) |
| Infection other than CDI | 8 (6) |
| CDI recurrence | 3 (2) |
| Otherc | 30 (20) |
| Deaths | |
| Unrelated to FMT | 4 (3) |
| Related to FMT | 0 (0) |
AV, arteriovenous; MRSA, methicillin-resistant Staphylococcus aureus.
Note some participants had more than 1 diagnosis or reason for hospitalization.
All other conditions were n = 1: abdominal aortic aneurysm, Barrett’s esophagus, belching, cardiovascular disease, chronic obstructive pulmonary disease, colon cancer, dermatitis, fistula between Indiana pouch and bowel, gastroesophageal reflux disease, hair loss, jaw cancer, left heart failure, left inguinal hernia, neurologic disorder, osteopenia, osteoporosis, overflow diarrhea, pelvis floor dysfunction, pregnancy, prostate cancer, snoring, and UTI.
Other reasons for hospitalization included acute episode of croup, acute right anterior cerebral artery stroke, breast implant removal, breathing, cirrhosis, colitis, constipation, Crohn’s disease flare, dehydration (2 cases), diverticulitis, abnormal liver function tests, fainting, hysterectomy, intestinal obstruction, lung transplant symptoms, overflow diarrhea, peritoneal dialysis catheter placement, potential ulcerative colitis flare, primary sclerosing cholangitis flare (worsening of left hepatic biliary duct inflammation), robotic prostatectomy, seizure, severe sepsis/septic shock, surgery for recurrent colon cancer, ulcerative colitis flare, ulcerative colitis laparoscopic ileal pouch anal anastomosis with ileostomy, urinary retention, UTI, vomiting, and weakness.