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. 2021 Mar 12;49(6):3003–3019. doi: 10.1093/nar/gkab146

Graphical Abstract.

Graphical Abstract

CcaF1 protein(red) binds to the ccaF1-ccsR1-4 transcript and together with RNase E contributes to maturation of the CcsR1-4 RNAs. Decreased RNase E activity or excess of CcaF1 impede this maturation. By acting on CcsR maturation CcaF1 contributes to the oxidative stress response. CcaF1 also binds to several other cellular RNAs suggesting its influence also on other physiological processes.