Table 1.
Summary of protein–protein interactions between OZ2 and mitochondrial splice factors. Y2H = yeast two-hybrid; BiFC = bimolecular fluorescence complementation
| Splicing factor | Target introns | OZ2 interaction (Y2H) | OZ2 interaction (BiFC) |
|---|---|---|---|
| ABO5 | nad2-i3* | Yes | Yes |
| BIR6 | nad7-i1 | Yes | Yes |
| MAT2 | cox2, nad1-i2, nad7-i2* | No | Yes |
| mCSF1 | rps3*, nad2-i3*, nad5-i1*, -i2*, -i3*, nad7-i2* and others | No | Yes |
| MISF26 | nad2-i3* | Yes | Yes |
| MISF74 | nad1-i4, nad2-i4 | No | No |
| mTERF15 | nad2-i3* | No | No |
| MTL1 | nad7-i2* | No | Yes |
| OTP439 | nad5-i2* | No | No |
| PMH2 | nad5-i1*, -i2*, -i3*, rps3* and others | Yes | Yes |
| RUG3 | nad2-i2, nad2-i3* | No | No |
| SLO3 | nad7-i2* | No | No |
| WTF9 | rpl2, ccmFc | No | No |
*Splice sites targeted by OZ2.