TABLE 1.
Clinicopathological characteristics of colorectal neuroendocrine tumors
| All | NET G1 | NET G2 | P value | ||
|---|---|---|---|---|---|
| Age | 59.0 (17‐86) | 63.5 (38‐79) | .20 | ||
| Gender | Male:female | 238:152 (39.0%) | 213:145 (40.5%) | 25:7 (21.9%) | .039 |
| Location | Upper rectum or more oral side:lower rectum | 54:334 (86.1%) | 45:311 (87.4%) | 9:23 (71.9%) | .028 |
| Size (mm) | <10:10≤ | 300:89 (22.9%) | 288:70 (19.6%) | 12:19 (61.3%) | <.0001 |
| Depressed lesion | Negative:positive | 273:71 (20.6%) | 258:56 (17.8%) | 15:15 (50.0%) | .0002 |
| Liver metastasis | Negative:positive | 387:3 (0.8%) | 357:1 (0.3%) | 30:2 (6.3%) | .019 |
| Depth of invasion | pT1:pT2≤ | 365:16 (4.2%) | 341:9 (2.6%) | 24:7 (22.6%) | <.0001 |
| Lymph node metastasis | Negative:positive | 317:54 (14.6%) | 301:40 (11.7%) | 16:14 (46.7%) | <.0001 |
| Lymphatic infiltration | Negative:positive | 306:53 (14.8%) | 289:41 (12.4%) | 17:12 (41.4%) | .0002 |
| Venous infiltration | Negative:positive | 280:78 (21.8%) | 269:61 (18.5%) | 11:17 (60.7%) | <.0001 |
| Chromogranin A | Negative:positive | 82:218 (72.7%) | 75:197 (72.4%) | 7:21 (75.0%) | 1 |
| Synaptophysin | Negative:positive | 22:271 (92.5%) | 21:245 (92.1%) | 2:26 (92.9%) | 1 |
Abbreviations: G, grade; NET, neuroendocrine tumor.