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. 2021 Apr 9;16(4):e0248984. doi: 10.1371/journal.pone.0248984

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© 2021 Kafita et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (a) Overall survival comparison within cancer types between patients afflicted with high-ELF4 tumours and those afflicted with low-ELF4 tumours. Compared to the patients with low-ELF4 tumours, the red boxplots indicate median OS durations that are shorter for the patients with high-ELF4 tumours; the blue indicates median OS durations that are longer for the patients with high-ELF4 whereas the grey boxplots indicate median OS periods that are undefined (undefined median DFS period in that > 50% of patients survived beyond the study duration). On each box, the centre mark shows the median, and the left and right edges of the box show the 25th and 75th percentiles, respectively. The whiskers extend to the most extreme data points that are not outliers, and the outliers are shown individually using the ’+’ symbol. (b) shows the percentage of the total number of patients with tumours with each group given the colours of the bars. The number of patients with tumours labels the marks expressed high ELF4 and low ELF4 transcripts. TCGA disease codes and abbreviations: UCEC, uterine corpus endometrial carcinoma; SKCM, skin cutaneous melanoma; BLCA, bladder urothelial carcinoma; UCS, uterine carcinosarcoma; OV, ovarian serous cystadenocarcinoma; LUSC, lung squamous cell carcinoma; STAD, stomach adenocarcinoma; LUAD, lung adenocarcinoma; ESCA, oesophageal adenocarcinoma; DLBC, diffuse large b-cell lymphoma; CESC, cervical squamous cell carcinoma; HNSC, head and neck squamous cell carcinoma; SARC, sarcoma; LIHC, liver hepatocellular carcinoma; BRCA, breast invasive carcinoma; COADREAD, colorectal adenocarcinoma; CHOL, cholangiocarcinoma; ACC, adrenocortical carcinoma; PAAD, pancreatic adenocarcinoma; PRAD, prostate adenocarcinoma; GBM, glioblastoma multiforme; KIRP, kidney renal papillary cell carcinoma; KIRC, kidney renal clear cell carcinoma; MESO, mesothelioma; LGG, brain lower grade glioma; UVM, uveal melanoma; PCPG, pheochromocytoma and paraganglioma; TGCT, testicular germ cell tumours; KICH, kidney chromophobe; THYM, thymoma; LAML, acute myeloid leukaemia; THCA, thyroid carcinoma.