Table 4.
AD Age ≤60 years (n=6) | HC Age ≤60 years (n=13) | P | AD Age >60 years (n=9) | HC Age >60 years (n=11) | P | |
---|---|---|---|---|---|---|
Anterior cingulate | 1.63±0.12 | 1.67±0.05 | 0.348 | 1.61±0.28 | 1.71±0.19 | 0.366 |
Brain stem | 1.73±0.16 | 1.84±0.06 | 0.037 | 1.71±0.14 | 1.91±0.18 | 0.012 |
Caudate nucleus | 1.34±0.44 | 1.98±0.18 | 0.0003 | 1.49±0.37 | 1.93±0.27 | 0.006 |
White matter | 1.44±0.19 | 1.40±0.08 | 0.473 | 1.52±0.19 | 1.48±0.18 | 0.603 |
Entorhinal cortex | 1.52±0.21 | 1.51±0.08 | 0.875 | 1.73±0.36 | 1.69±0.24 | 0.782 |
Frontal cortex | 1.22±0.18 | 1.25±0.04 | 0.516 | 1.36±0.21 | 1.28±0.13 | 0.284 |
Fusiform gyrus | 1.55±0.22 | 1.40±0.05 | 0.032 | 1.73±0.17 | 1.48±0.20 | 0.009 |
Hippocampus | 1.84±0.38 | 2.01±0.11 | 0.147 | 1.85±0.31 | 2.14±0.22 | 0.030 |
Inferior temporal cortex | 1.60±0.21 | 1.37±0.04 | 0.001 | 1.86±0.32 | 1.48±0.21 | 0.006 |
Lingual gyrus | 1.26±0.22 | 1.20±0.06 | 0.415 | 1.33±0.14 | 1.22±0.14 | 0.084 |
Middle temporal gyrus | 1.44±0.18 | 1.27±0.04 | 0.003 | 1.61±0.31 | 1.34±0.16 | 0.022 |
Occipital cortex | 1.35±0.17 | 1.16±0.05 | 0.001 | 1.42±0.15 | 1.18±0.12 | 0.001 |
Pallidum | 2.19±0.60 | 2.49±0.15 | 0.095 | 2.53±0.38 | 3.01±0.55 | 0.040 |
Parahippocampal gyrus | 1.98±0.37 | 1.78±0.09 | 0.082 | 2.04±0.26 | 1.90±0.23 | 0.209 |
Parietal cortex | 1.23±0.26 | 1.16±0.04 | 0.382 | 1.34±0.16 | 1.18±0.11 | 0.013 |
Posterior cingulate | 1.68±0.24 | 1.45±0.06 | 0.004 | 1.69±0.24 | 1.49±0.15 | 0.038 |
Precuneus | 1.42±0.27 | 1.26±0.03 | 0.045 | 1.47±0.18 | 1.26±0.11 | 0.006 |
Putamen | 1.92±0.37 | 2.05±0.08 | 0.224 | 2.18±0.31 | 2.33±0.39 | 0.358 |
Thalamus | 1.47±0.61 | 2.11±0.11 | 0.001 | 1.86±0.37 | 2.26±0.28 | 0.013 |
AD: Alzheimer’s disease; HC: Healthy controls