Table 9.
THK 5351 standardized uptake value ratio s cut off for each brain area
| Region of interest | SUVR cut off | Sensitivity | Specificity |
|---|---|---|---|
| Anterior cingulate | 1.56 | 93.33 | 4.17 |
| Brain stem | 1.62 | 80 | 4.17 |
| Caudate nucleus | 1.67 | 40 | 4.17 |
| White matter | 1.37 | 80 | 25 |
| Entorhinal cortex | 1.25 | 100 | 4.17 |
| Frontal cortex | 1.03 | 93.33 | 4.17 |
| Fusiform gyrus | 1.5* | 80 | 87.5 |
| Hippocampus | 1.75 | 66.67 | 4.17 |
| Inferior temporal cortex | 1.5* | 80 | 83.33 |
| Lingual gyrus | 1.16 | 80 | 25 |
| Middle temporal gyrus | 1.31* | 86.67 | 66.67 |
| Occipital cortex | 1.31* | 80 | 87.5 |
| Pallidum | 2.21 | 73.33 | 4.17 |
| Parahippocampal gyrus | 1.78 | 80 | 29.17 |
| Parietal cortex | 1.11 | 80 | 16.67 |
| Posterior cingulate | 1.53* | 80 | 79.17 |
| Precuneus | 1.32* | 80 | 83.33 |
| Putamen | 1.75 | 80 | 4.17 |
| Thalamus | 1.9 | 46.67 | 4.17 |
*Selected optimum cut-offs at a sensitivity level ≥80% and the highest specificity level. SUVR: Standardized uptake value ratio