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. 2021 Apr 9;7(15):eabf6780. doi: 10.1126/sciadv.abf6780

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Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 3 — (A) Alcohol wanting ratings of alcohol cues were lower in KD than SA after diet initiation. (B) There were no group differences for wanting ratings caused by food cues. (C) There was a significant group × time for brain reactivity to alcohol > neutral cues in dACC (P_FWE < 0.05) with (D) increased dACC reactivity in KD > SA in week 3 > week 1. (E) There was a significant group × time for brain reactivity to food > neutral cues in dACC (P_FWE < 0.05) with (F) elevated dACC reactivity in KD > SA in week 3 > week 1. *P < 0.05 and **P < 0.01, difference between KD and SA; #P < 0.09, a trend effect compared with KD. Photo credit: Corinde Wiers, NIH/NIAAA.