Table 1. Anthropometric and biochemical characteristics of Cohort 1.
Characteristics (mean ± SE) | YOUNG (N° 35, age range 24-39) | OLD1 (N° 57, age range 60-69) | OLD2 (N° 33, age range 70-79) | OLD3 (N° 26, age range 85-99) | CENTENARIANS (N° 38, age range 100-107) | ||||||||||
18 F | 17 M | p value | 37 F | 20 M | p value | 16 F | 17 M | p value | 13 F | 13 M | p value | 21 F | 17 M | p values | |
cPlin2 (ng/ml) | 35.25 ± 4.38 |
22.63 ± 4.37 |
0.038 | 50.46 ± 2.76 |
30.63 ± 3.43 |
0.000 | 67.22 ± 5.39 |
28.34 ± 4.60 |
0.000 | 35.55 ± 7.55 |
30.89 ± 7.80 |
n.s. | 30.98 ± 5.77 |
32.07 ± 4.97 |
n.s. |
BMI | 21.63 ± 0.49 |
26.13 ± 1.06 |
0.001 | 29.56 ± 0.75 |
31.72 ± 1.06 |
n.s. | 30.11 ± 1.39 |
28.66 ± 0.89 |
n.s. | 25.51 ± 0.86 |
28.31 ± 1.54 |
n.s. | 24.18 ± 0.96 |
24.47 ± 0.70 |
n.s. |
Waist circumference (cm) | 70.79 ± 0.87 |
85.13 ± 3.60 |
0.000 | 95.99 ± 1.78 |
107.0 ± 2.68 |
0.001 | 95.83 ± 3.66 |
99.62 ± 2.23 |
n.s. | --- | --- | n.s. | 79.42 ± 2.32 |
92.40 ± 3.04 |
0.001 |
Hip circumference (cm) |
98.36 ± 1.28 |
98.81 ± 2.40 |
n.s. | 107.77 ± 1.70 |
109.75 ± 2.20 |
n.s. | 110.97 ± 2.85 |
104.97 ± 2.23 |
n.s. | --- | --- | n.s. | 93.70 ± 2.24 |
98.20 ± 2.53 |
n.s. |
Handgrip (kg) | 30.18 ± 1.02 |
47.50 ± 2.5 |
0.000 | 23.0 ± 1.03 |
42.33 ± 2.6 |
0.024 | 22.25 ± 1.82 |
30.33 ± 1.71 |
0.006 | 20.17 ± 1.85 |
17.88 ± 2.32 |
n.s. | 12.15 ± 1.24 |
18.44 ± 1.19 |
0.002 |
Glycaemia (mg/dl) | 82.73 1.77 |
85.83 ± 1.16 |
n.s. | 131.68 ± 6.24 |
144.15 ± 13.17 |
n.s. | 112.06 ± 9.86 |
119.06 ± 9.44 |
n.s. | 80.92 ± 4.50 |
90.38 ± 8.52 |
n.s. | 86.05 ± 2.55 |
86.41 ± 3.89 |
n.s. |
Total cholesterol (mg/dl) | 185.80 ± 7.42 |
194.0 ± 12.83 |
n.s. | 205.46 ± 5.92 |
201.10 ± 8.08 |
n.s. | 208.13 ± 7.61 |
202.29 ± 10.72 |
n.s. | 192.85 ± 9.19 |
179.92 ± 11.08 |
n.s. | 201.29 ± 11.05 |
181.59 ± 9.97 |
n.s. |
HDL (mg/dl) | 63.0 ± 7.42 |
55.33 ± 5.70 |
n.s. | 53.70 ± 2.54 |
48.85 ± 2.28 |
n.s. | 61.69 ± 5.16 |
50.82 ± 4.50 |
n.s. | 66.62 ± 3.12 |
56.92 ± 5.55 |
n.s. | 51.29 ± 3.08 |
47.29 ± 3.28 |
n.s. |
LDL (mg/dl) | 111.33 ± 5.21 |
124.83 ± 9.71 |
n.s. | 126.16 ± 5.4 |
113.11 ± 5.82 |
n.s. | 113.52 ± 14.12 |
110.61 ± 12.10 |
n.s. | 104.78 ± 7.91 |
101.92 ± 9.18 |
n.s. | 120.95 ± 9.28 |
106.67 ± 11.90 |
n.s. |
Triglycerides (mg/dl) | 57.87 ± 4.23 |
69.83 ± 12.52 |
n.s. | 131.22 ± 19.51 |
136.9 ± 23.58 |
n.s. | 130.81 ± 9.47 |
159.47 ± 29.78 |
n.s. | 107.23 ± 10.32 |
104.38 ± 9.51 |
n.s. | 116.95 ± 6.75 |
98.94 ± 8.71 |
0.048 |
Average number of diseases | 0 | 1.46 | 1.57 | 0.84 | 0.60 | ||||||||||
Current diseases | angina pectoris (1), diabetes (36), hepatitis (1), hypercholesterolemia (13), hypertension (32) | angina pectoris (1), diabetes (13), heart failure (1), hepatitis (1), hypercholesterolemia (11), hypertension (24), obliterative arteriopathy (1) | diabetes (2), heart failure (3), hypercholesterolemia (3), hypertension (12), Irregular heart rhythm (2) | Angina pectoris (3), diabetes (3), heart failure (9), hypercholesterolemia (3), hypertension (5) |
Legend: n.s. = not significant.