Table 2. Comparison of organ metastasis patterns stratified by age patients with metastatic renal cell carcinoma.
Parameter | ≤ 67 years | Percentage | 68-80 years | Percentage | > 80 years | Percentage | P-value |
n=5620 | 100.0% | n=2808 | 100.0% | n=1153 | 100.0% | ||
Lung metastasis only | 1923 | 34.2% | 943 | 33.6% | 379 | 32.9% | 0.631 |
bone metastasis only | 1278 | 22.7% | 398 | 14.2% | 79 | 6.9% | <0.001 |
Brain metastasis only | 152 | 2.7% | 72 | 2.6% | 18 | 1.6% | 0.078 |
Liver metastasis only | 384 | 6.8% | 168 | 6.0% | 53 | 4.6% | 0.012 |
Lung and brain | 171 | 3.0% | 121 | 4.3% | 86 | 7.5% | <0.001 |
Lung and bone | 644 | 11.5% | 449 | 16.0% | 190 | 16.5% | <0.001 |
Bone and brain | 85 | 1.5% | 12 | 0.4% | 4 | 0.3% | <0.001 |
Bone and liver | 176 | 3.1% | 59 | 2.1% | 20 | 1.7% | 0.002 |
Lung and liver | 333 | 5.9% | 260 | 9.3% | 169 | 14.7% | <0.001 |
Brain and liver | 7 | 0.1% | 13 | 0.5% | 4 | 0.3% | 0.011 |
Lung, bone and brain | 110 | 2.0% | 88 | 3.1% | 40 | 3.5% | <0.001 |
Lung, bone and liver | 250 | 4.4% | 157 | 5.6% | 87 | 7.5% | <0.001 |
Lung, brain and liver | 42 | 0.7% | 26 | 0.9% | 24 | 2.1% | <0.001 |
Bone, brain, and liver | 10 | 0.2% | 0 | 0.0% | 0 | 0.0% | 0.029 |
Lung, bone, brain, and liver | 55 | 1.0% | 42 | 1.5% | 0 | 0.0% | <0.001 |