Table 2. Integrated enrichment analysis of the metabolome and transcriptome data.

Pathway	Total	Count	P-value	Impact
Valine, leucine and isoleucine biosynthesis	8	2	0.002	0.429
Glycerophospholipid metabolism	34	3	0.003	0.500
Phenylalanine metabolism	11	2	0.004	0.600
Glycosylphosphatidylinositol-anchor biosynthesis	3	1	0.028	0.143
Phenylalanine, tyrosine and tryptophan biosynthesis	4	1	0.037	1.000
Arachidonic acid metabolism	37	2	0.045	0.472
Linoleic acid metabolism	5	1	0.046	0.250
Valine, leucine and isoleucine degradation	38	2	0.048	0.093
Aminoacyl-tRNA biosynthesis	46	2	0.067	0.044
alpha-Linolenic acid metabolism	13	1	0.117	0.083
Sphingolipid metabolism	21	1	0.182	0.550
Biosynthesis of unsaturated fatty acids	22	1	0.190	0.048
Tryptophan metabolism	40	1	0.320	0.051
Pyrimidine metabolism	41	1	0.327	0.083
Purine metabolism	68	1	0.485	0.014