Table 1B. Comparative transcriptomic analyses between bat, human, mouse.
Gene | Bat | Human | Mouse |
PIK3CA | 0.483 | -0.233 | -0.568 |
ROCK1 | 0.468 | -0.091 | -0.41 |
RB1CC1 | 0.446 | -0.143 | -0.164 |
CSNK2A1 | 0.415 | -0.015 | -0.406 |
NEDD4 | 0.383 | -0.043 | -0.1 |
PAFAH1B2 | 0.293 | -0.278 | -0.097 |
USP33 | 0.278 | -0.237 | -0.165 |
TRAPPC8 | 0.274 | -0.167 | -0.066 |
ULK2 | 0.271 | -0.017 | -0.312 |
SIRT1 | 0.243 | -0.091 | -0.566 |
SNX14 | 0.214 | -0.27 | -0.158 |
VTA1 | 0.208 | -0.302 | -0.327 |
MAP3K7 | 0.203 | -0.213 | -0.247 |
TBK1 | 0.198 | -0.218 | -0.215 |
VPS36 | 0.179 | -0.207 | -0.483 |
NRBF2 | 0.177 | -0.236 | -0.361 |
DNM1L | 0.168 | -0.081 | -0.245 |
UBXN2B | 0.146 | -0.14 | -0.179 |
EIF2AK4 | 0.141 | -0.069 | -0.361 |
SH3GLB1 | 0.132 | -0.149 | -0.039 |
PIK3R4 | 0.11 | -0.227 | -0.457 |
ATP6V1H | 0.099 | -0.172 | -0.032 |
PIK3C3 | 0.077 | -0.268 | -0.269 |
RAB3GAP1 | 0.053 | -0.013 | -0.567 |
ATP6V1C1 | 0.03 | -0.186 | -0.09 |
U2AF1 | 0.03 | -0.053 | -0.207 |
(A) Comparison of the pathway expression pattern for autophagy-associated GO terms. Within each species, the median of the Spearman’s correlation coefficients of all genes under each of enriched age-associated GO terms was used to represent their overall expression pattern with age. The values behind the GO terms indicate the number of genes enriched. (B) The autophagy associated genes that exhibited the opposite direction of expression changes with age in bat compared to human and mouse are shown. Values indicate the Spearman’s correlation coefficients between gene expression and age for each species.