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Dyadic geometry differences between HPF and CFD samples. Histograms showing the distribution (%) of the surface area associated with different dyadic spacing (minimum distance between TT and jSR) in ventricular tissue or cells from rabbit (left) and mouse (right), preserved by CFD or HPF. Dyad defined as space of jSR-TT apposition of ≤20 nm. Pooled data from n = 20 TT-jSR pairs/ 16–20 cells/ 3 hearts (rabbit); n = 21–23 TT-jSR pairs/ 14–21 cells/ 2–3 hearts (mouse).
