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. 2021 Jan 28;41(4):1403–1413. doi: 10.1007/s10792-021-01692-6

Table 6.

Correlation between tear inflammatory molecules and clinical symptoms in both groups before cataract surgery

NIKTMH NIF-BUT NIAvg-BUT Redness score Meibography score Schirmer I test
IL-1β r 0.097 −0.175 −0.048 0.146 −0.085 0.276
P value 0.433 0.154 0.698 0.239 0.493 0.023
IL-6 r 0.03 0.257 −0.169 0.079 0.151 −0.096
P value 0.777 0.012 0.104 0.456 0.143 0.354
IL-8 r −0.035 −0.204 −0.137 0.153 0.076 0.200
P value 0.731 0.043 0.176 0.136 0.453 0.046
IL-10 r −0.037 0.096 0.123 −0.012 −0.003 −0.158
P value 0.717 0.346 0.227 0.905 0.973 0.119
IL-12 r −0.097 −0.079 −0.044 0.05 −0.064 −0.022
P value 0.343 0.441 0.667 0.629 0.533 0.827
TNF-α r 0.228 −0.105 −0.018 −0.048 −0.221 −0.153
P value 0.056 0.382 0.88 0.696 0.062 0.197
ICAM-1 r −0.094 −0.027 −0.104 0.003 0.108 0.152
P value 0.375 0.795 0.326 0.98 0.303 0.146

IL interleukin; TNF tumor necrosis factor; ICAM intercellular cell adhesion molecule; NIKTMH noninvasive keratography tear meniscus height; NIF-BUT noninvasive first breakup time; NIAvg-BUT noninvasive average breakup time; OSDI Ocular Surface Disease Index. Spearman correlation coefficient (r) was used to analyze the associations between variables. Significant correlations are in bold