TABLE I.
Demographic and clinical characteristics of study population
| Characteristic | Control | CRSwNP | AERD | P value (CRSwNP vs AERD) |
|---|---|---|---|---|
| No. | 64 | 109 | 30 | |
| Age (y) | 51.6 ± 15.4 | 50.4 ± 15.2 | 47.8 ± 11.5 | .31 |
| Sex: female, n (%) | 40 (68) | 35 (32) | 12 (40) | .51 |
| Asthma, n (%) | 1 (2) | 37 (33.9) | 30 (100) | <.001 |
| Allergic rhinitis, n (%) | 5 (8) | 64 (58.7) | 23 (76.7) | .27 |
| Prior surgery, n (%) | 0 (0) | 40 (36.7) | 21 (70) | .02 |
| BMI (kg/m2) | 33.1 ± 9.1 | 29.1 ± 5.9 | 29.8 ± 4.7 | .65 |
| NCS, n (%) | 1 (2) | 90 (82.6) | 23 (76.7) | .75 |
| LTR, n (%) | 3(5) | 26 (23.9) | 19 (63.3) | <.001 |
| Current smoker, n (%) | 1 (2) | 5 (4.6) | 0 (0) | .24 |
| SNOT-22 score | 42.1 ± 21.1 | 50.7 ± 21.6 | .08 | |
| Rhinologic | 12.3 ± 5.7 | 15.0 ± 5.5 | .04 | |
| Extranasal | 7.2 ± 3.5 | 9.2 ± 3.2 | .01 | |
| Ear/facial | 7.0 ± 5.3 | 9.3 ± 5.5 | .08 | |
| Psychological | 11.5 ± 8.9 | 12.7 ± 8.0 | .56 | |
| Sleep | 10.3 ± 7.1 | 10.8 ± 7.9 | .77 | |
| CT score | 15.9 ± 4.2 | 20.3 ± 3.5 | <.001 |
AERD, Aspirin-exacerbated respiratory disease; BMI, body mass index; CT, computed tomography; LTR, leukotriene modifier; NCS, nasal corticosteroid.
Values are presented as means ± SDs or medians with interquartile ranges, depending on the normalcy of the data. Differences between groups were assessed by using the Kruskal-Wallis test or χ2 analysis. Boldface text indicates a P value of less than .05.