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. 2021 Apr 9;7:73. doi: 10.1038/s41420-021-00463-7

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A The glycogen content after lncRNA-FKBP1C overexpression prepared with lentivirus and intramuscularly injected into the gastrocnemius muscle. B The enzyme activity of LDH and SDH. C Immunohistochemistry analyses of gastrocnemius muscle fiber infected with LV-lncRNA-FKBP1C or LV-NC. D The data are showed as MYH1A and MYH7B protein content. E Hematoxylin and eosin (H&E) staining of gastrocnemius muscle. F The distribution of muscle fiber cross sectional area (n = 6 per group). G The mRNA level of several fast muscle genes and slow muscle genes. H The glycogen content after infected with LV-shRNA-lncRNA-FKBP1C or LV-shRNA-NC. I The enzyme activity of LDH and SDH. J Immunohistochemistry analyses of gastrocnemius muscle fiber. K The MYH1A and MYH7B protein content. L Hematoxylin and eosin (H&E) staining of gastrocnemius muscle. M The distribution of muscle fiber cross sectional area (n = 6 per group). N The mRNA level of several fast muscle genes and slow muscle genes. Results are shown as mean ± S.E.M. and the data are representative of at least three independent assays. Independent sample t-test was used to analyze the statistical differences between groups (*P < 0.05, **P < 0.01, ***P < 0.001).