Table 3.

Importance of social RDoC features in distinguishing ASD.

Feature	ASD vs. TD Cohen’s D	DCD vs. TD Cohen’s D	ASD vs. DCD Cohen’s D	ASD vs. TD selection frequency	ASD vs. DCD selection frequency
SRS total	3.90	1.56	2.01	NA	NA
SRS social comm. and interaction	3.73	1.48	1.92	NA	NA
SRS social communication	3.52	1.35	1.95	NA	NA
SRS social cognition	2.91	1.06	1.39	NA	NA
SRS awareness	2.70	0.89	1.90	NA	NA
SRS social motivation	2.17	0.93	1.18	NA	NA
SCQ total	1.65	0.58	1.29	1	0.896
CBCL total competence	− 1.61	− 0.48	− 0.98	1	0.2835
CBCL SS social problems	2.00	1.39	0.68	1	0.0045
SCQ recip. social interaction	1.17	0.35	0.89	0.9245	0.057
CBCL SS rule-breaking behavior	0.93	0.77	0.20	0.216	0
SCQ communication	0.83	0.44	0.56	0.097	0
NEPSY ToM total	− 0.75	0.08	− 0.79	0.06	0.0425
NEPSY ToM verbal	− 0.71	0.06	− 0.73	0.0195	0.011
Alexithymia communication	0.46	− 0.08	0.59	0.0005	0.0035
Alexithymia total	0.53	0.15	0.33	0	0
Alexithymia identification	0.38	0.30	0.09	0	0
IRI personal distress	0.34	0.28	0.07	0	0
Alexithymia external thinking	0.23	0.08	0.10	0	0
IRI fantasy scale	0.15	0.16	− 0.02	0	0
EmQue affective	0.13	0.55	− 0.33	0	0
NESPY affect recognition	− 0.45	− 0.18	− 0.23	0	0
LOI how hands	− 0.35	− 0.21	− 0.09	0	0
LOI why hands	− 0.33	− 0.36	0.01	0	0
IRI perspective taking	− 0.32	− 0.13	− 0.21	0	0
LOI why face	− 0.27	− 0.30	0.01	0	0
LOI how face	− 0.24	0.04	− 0.27	0	0
EmQue prosocial motiv	− 0.22	0.12	− 0.33	0	0
IRI empathic concern	− 0.19	0.10	− 0.29	0	0
EmQue cognitive	− 0.17	− 0.04	− 0.11	0	0
NEPSY ToM contextual	− 0.12	0.23	− 0.41	0	0
IRI total	0.00	0.15	− 0.16	0	0

The first three columns report Cohen’s d effect size from paired comparisons between subject groups. The last two columns report selection frequency of each feature by univariate feature selection for the full RDoC + M + S feature set across all 2000 cross validation loops for each of our two decoders (ASD vs. TD and ASD vs. DCD). Social features (rows) sorted by selection frequency. In CBCL features, SS = syndrome scale.