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. Author manuscript; available in PMC: 2021 May 26.
Published in final edited form as: Genet Med. 2020 Nov 26;23(4):751–757. doi: 10.1038/s41436-020-01035-3

Figure 3.

Figure 3.

Correlation of NEFL levels with clinical outcome measures, by assay method. Forest plot indicates the correlation coefficients along with 95% confidence limits. The horizontal axes describe the magnitude of the correlation coefficients, with <0 suggesting inverse relations and >0 suggesting positive relations. Adjusted p values are derived from the Stepdown Bonferroni method for multiple comparisons. Bold – p<.05. Bold italics – p<.01. ABC: adaptive behavior composite. CGI: clinical global impression. Cr: creatine. CSF: cerebrospinal fluid. Glx: glutamatergic metabolites. NAA: N-acetylaspartate. NEFL: neurofilament light chain. PEA: proximal extension assay. Simoa™: single molecule array. UBDRS: Unified Batten Disease Rating Scale.