Skip to main content
. Author manuscript; available in PMC: 2021 Sep 10.
Published in final edited form as: Nature. 2021 Mar 10;592(7853):309–314. doi: 10.1038/s41586-021-03314-8

Extended Data Fig. 10 |. TF/cofactor interaction “circuits”.

Extended Data Fig. 10 |

TF genes are indicated with capitalized gene names and are connected to their encoded TFs (spheres). Arrows connect TFs to other TF-encoding genes to which they are bound via their cognate motif. TFs that bound to their own genes or created a loop used blue arrows (light blue where a motif was not detected for TFs binding their own gene). TFs are color-coded based on their meta-assemblage membership (see key). Those TFs that are also particularly enriched with cofactors have colored halos. Short diagonal arrows point to the total number of all ~6,000 coding genes that are bound by that TF to its cognate motif (first number) or where no motif was detected (second number). Average relative PIC (TFIIB/Sua7) occupancy levels for those sets of genes is indicated by (•) count.