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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Eur J Epidemiol. 2021 Jan 11;36(3):275–285. doi: 10.1007/s10654-020-00707-3

Table 3.

Association between physical activity (PA) and all-cause mortality using different analytical approaches stratified by PA levels (pooled results of Nurses’ Health Study and Health Professionals Follow-up Study, 1986–2014)

Hazard ratio (95% Cl) per 10 MET-hour/week
Physical activity 0–50 MET-hour/week 50–150 MET-hour/week
Single measure of PA
 Baseline1 0.95 (0.94–0.96) 1.00 (0.98–1.02)
 Simple update2 0.78 (0.77–0.79) 1.00 (0.99–1.02)
 2-yr lag3 0.85 (0.84–0.86) 0.99 (0.98–1.01)
 4-yr lag3 0.85 (0.84–0.86) 1.00 (0.98–1.02)
 8-yr lag3 0.86 (0.85–0.87) 0.99 (0.97–1.01)
 12-yr lag3 0.88 (0.87–0.89) 0.99 (0.97–1.01)
Repeated measures of PA
 Cumulative average4 0.87 (0.86–0.88) 0.99 (0.96–1.02)
 2-yr lag5 0.90 (0.89–0.91) 0.97 (0.94–0.99)
 4-yr lag5 0.91 (0.90–0.92) 0.97 (0.94–1.00)
 8-yr lag5 0.92 (0.91–0.93) 0.96 (0.93–0.99)
 12-yr lag5 0.93 (0.92–0.94) 0.96 (0.93–1.00)

All models adjusted for the same covariates for model 3 (fully adjusted model) in Table 2.

1

Physical activity measured at baseline in 1986;

2

Physical activity measured closest (most recent) to death;

3

Physical activity measured 2, 4, 8 or 12 years prior to death;

4

Average of repeated measures of physical activity from baseline to death;

5

Average of repeated measures of physical activity measured 2, 4, 8 or 12 years prior to death.